Cimetidine Tablets and Delavirdine Mesylate
Determining the interaction of Cimetidine Tablets and Delavirdine Mesylate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using delavirdine together with cimetidine is not recommended. By reducing stomach acid, cimetidine can decrease the absorption and blood levels of delavirdine and make the medication less effective against HIV. Your doctor or pharmacist may be able to offer suggestions on safer alternatives if you require treatment for stomach acid or ulcer while you are being treated with delavirdine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Theoretically, H2 antagonists and proton pump inhibitors may decrease the gastrointestinal absorption of delavirdine. The proposed mechanism is a pH-dependent reduction in drug dissolution or absorption.
MANAGEMENT: While the clinical significance of this potential interaction is unknown, the manufacturer recommends against the chronic use of these drugs with delavirdine due to the risk of treatment failure and emergence of drug resistance associated with subtherapeutic levels of delavirdine.
- "Product Information. Rescriptor (delavirdine)." Pharmacia and Upjohn, Kalamazoo, MI.
Generic Name: cimetidine
Brand name: Tagamet HB, Tagamet
Synonyms: Cimetidine
Generic Name: delavirdine
Brand name: Rescriptor
Synonyms: Delavirdine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cimetidine Tablets-Delestrogen
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- Cimetidine Tablets-Delos Lotion
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- Delavirdine Mesylate-Cimzia
- Delavirdine Mesylate-Cimzia (Certolizumab Prefilled Syringes)
- Delavirdine Mesylate-Cimzia (Certolizumab Vials)
- Delavirdine Mesylate-Cinacalcet
- Delavirdine Mesylate-Cinacalcet Hydrochloride
- Delavirdine Mesylate-Cinobac