Cimetidine Tablets and Kaletra (Lopinavir and Ritonavir Tablets)
Determining the interaction of Cimetidine Tablets and Kaletra (Lopinavir and Ritonavir Tablets) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Coadministration with inhibitors of CYP450 3A4 may increase the plasma concentrations of lopinavir, which is primarily metabolized by the isoenzyme. The magnitude and clinical significance of this interaction are unknown, particularly when in the presence of ritonavir as a pharmacokinetic booster. Limited data indicate that ketoconazole, a potent CYP450 3A4 inhibitor, does not substantially alter the plasma concentrations of lopinavir administered as lopinavir-ritonavir in a 4:1 ratio.
- "Product Information. Kaletra (lopinavir-ritonavir)" Abbott Pharmaceutical, Abbott Park, IL.
Generic Name: cimetidine
Brand name: Tagamet HB, Tagamet
Synonyms: Cimetidine
Generic Name: lopinavir / ritonavir
Brand name: Kaletra
Synonyms: Kaletra
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cimetidine Tablets-Kaletra Oral Solution
- Cimetidine Tablets-Kalexate
- Cimetidine Tablets-Kalexate Powder
- Cimetidine Tablets-Kalliga
- Cimetidine Tablets-Kalosar
- Cimetidine Tablets-Kalydeco
- Kaletra (Lopinavir and Ritonavir Tablets)-Cimzia
- Kaletra (Lopinavir and Ritonavir Tablets)-Cimzia (Certolizumab Prefilled Syringes)
- Kaletra (Lopinavir and Ritonavir Tablets)-Cimzia (Certolizumab Vials)
- Kaletra (Lopinavir and Ritonavir Tablets)-Cinacalcet
- Kaletra (Lopinavir and Ritonavir Tablets)-Cinacalcet Hydrochloride
- Kaletra (Lopinavir and Ritonavir Tablets)-Cinobac