Cinacalcet Hydrochloride and Flextra

• Generic Name: cinacalcet
• Dosage Forms: n.a.
• Other Brand Names: Sensipar

Treatment of secondary hyperparathyroidism associated with chronic renal disease in patients who are undergoing hemodialysis or peritoneal dialysis.

Safety and efficacy in patients who are not undergoing dialysis have not been established.

May be used alone or in conjunction with vitamin D analogs and/or phosphate binders.

Effects on clinical outcomes remain to be fully determined. The primary finding of the EVOLVE trial (a lack of effect on mortality or major cardiovascular events ) is controversial because of study limitations.

Management of hypercalcemia associated with parathyroid carcinoma; designated an orphan drug by FDA for this use.

Treatment of hypercalcemia associated with primary hyperparathyroidism in patients who would be candidates for parathyroidectomy based on serum calcium concentrations but who are unable to undergo the surgery; designated an orphan drug by FDA for this use.

• Generic Name: acetaminophen / caffeine / phenyltoloxamine
• Dosage Forms: n.a.
• Other Brand Names:

  Flextra Plus

Flextra Plus contains a combination of acetaminophen, caffeine, and phenyltoloxamine. Acetaminophen is a pain reliever and fever reducer. Caffeine can help increase the pain relieving effects of acetaminophen. Phenyltoloxamine is an antihistamine that reduces the effects of natural chemical histamine in the body.

Flextra Plus is used to treat mild pain and discomfort caused by headache, muscle aches, back pain, tooth pain, menstrual pain, arthritis, or the common cold or flu.

Flextra Plus may also be used for purposes not listed in this medication guide.