Cinacalcet Hydrochloride and H.P. Acthar Gel

• Generic Name: cinacalcet
• Dosage Forms: n.a.
• Other Brand Names: Sensipar

Treatment of secondary hyperparathyroidism associated with chronic renal disease in patients who are undergoing hemodialysis or peritoneal dialysis.

Safety and efficacy in patients who are not undergoing dialysis have not been established.

May be used alone or in conjunction with vitamin D analogs and/or phosphate binders.

Effects on clinical outcomes remain to be fully determined. The primary finding of the EVOLVE trial (a lack of effect on mortality or major cardiovascular events ) is controversial because of study limitations.

Management of hypercalcemia associated with parathyroid carcinoma; designated an orphan drug by FDA for this use.

Treatment of hypercalcemia associated with primary hyperparathyroidism in patients who would be candidates for parathyroidectomy based on serum calcium concentrations but who are unable to undergo the surgery; designated an orphan drug by FDA for this use.

• Generic Name: corticotropin
• Dosage Forms: injection
• Other Brand Names:

  Acthar Gel, HP, Acthar, ACTH Gel, ACTH-80, ACTH-40 HP

Acthar Gel, H.P. is a hormone that is used to treat many different conditions such as multiple sclerosis, psoriatic or rheumatoid arthritis, ankylosing spondylitis, lupus, severe allergic reactions, breathing disorders, and inflammatory conditions of the eyes.

Acthar Gel, H.P. is also used to treat infantile spasms in children younger than 2 years old.

Acthar Gel, H.P. can reduce the symptoms of many disorders, but it is not a cure for these conditions. This medicine is also not expected to slow the progress of any disease.

Acthar Gel, H.P. may also be used for purposes not listed in this medication guide.