Cinacalcet Hydrochloride and PosiFlush flush

• Generic Name: cinacalcet
• Dosage Forms: n.a.
• Other Brand Names: Sensipar

Treatment of secondary hyperparathyroidism associated with chronic renal disease in patients who are undergoing hemodialysis or peritoneal dialysis.

Safety and efficacy in patients who are not undergoing dialysis have not been established.

May be used alone or in conjunction with vitamin D analogs and/or phosphate binders.

Effects on clinical outcomes remain to be fully determined. The primary finding of the EVOLVE trial (a lack of effect on mortality or major cardiovascular events ) is controversial because of study limitations.

Management of hypercalcemia associated with parathyroid carcinoma; designated an orphan drug by FDA for this use.

Treatment of hypercalcemia associated with primary hyperparathyroidism in patients who would be candidates for parathyroidectomy based on serum calcium concentrations but who are unable to undergo the surgery; designated an orphan drug by FDA for this use.

• Generic Name: heparin flush
• Dosage Forms: n.a.
• Other Brand Names: Heparin Lock flush, Monoject Prefill Advanced, PosiFlush

PosiFlush is an anticoagulant (blood thinner) that prevents the formation of blood clots.

PosiFlush is used to flush (clean out) an intravenous (IV) catheter, which helps prevent blockage in the tube after you have received an IV infusion.

PosiFlush should not be used to treat or prevent blood clots in the body. A separate this medicine product is available to use for this purpose.

PosiFlush may also be used for purposes not listed in this medication guide.