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Cipro Iv Minibags and Diazepam Oral Solution Concentrate

Determining the interaction of Cipro Iv Minibags and Diazepam Oral Solution Concentrate and the possibility of their joint administration.

Check result:
Cipro Iv Minibags <> Diazepam Oral Solution Concentrate
Relevance: 14.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

A pharmacokinetic interaction between ciprofloxacin and diazepam has been reported in one study. Patients pretreated with ciprofloxacin experienced a prolongation of the elimination half-life of diazepam and a decrease in the plasma clearance of diazepam. These alterations in the kinetic parameters of diazepam were not associated with alterations in the pharmacologic effects of diazepam. The clinical implications of these findings are unknown.

References
  • Kamali F, Thomas SH, Edwards C "The influence of steady-state ciprofloxacin on the pharmacokinetics and pharmacodynamics of a single dose of diazepam in healthy volunteers." Eur J Clin Pharmacol 44 (1993): 365-7
Cipro Iv Minibags

Generic Name: ciprofloxacin

Brand name: Cipro IV, Cipro, Cipro XR, Proquin XR

Synonyms: Cipro I.V. (injection)

Diazepam Oral Solution Concentrate

Generic Name: diazepam

Brand name: Valium, Diastat, Diastat AcuDial, Diastat Pediatric, Diazepam Intensol, Zetran

Synonyms: Diazepam

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.