Cipro Iv Minibags and Phenytoin

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using ciprofloxacin together with phenytoin can cause phenytoin to be less effective in preventing seizures. Talk with your doctor before using these medications together. You may need a dose adjustment or special tests to safely take these medications together. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Ciprofloxacin may increase or decrease plasma phenytoin concentrations during concomitant therapy, increasing the risk of phenytoin toxicity or seizures. In addition, quinolones may lower the seizure threshold. Although not clearly defined, suggested mechanisms for reduced phenytoin concentrations include ciprofloxacin inhibition of phenytoin renal tubular reabsorption resulting in increased phenytoin elimination or an effect by ciprofloxacin on intestinal flora that alters phenytoin enterohepatic recirculation. Other hydantoins may also be affected.

MANAGEMENT: Clinical monitoring of patient response, including serum hydantoin concentrations, is recommended when initiating or discontinuing ciprofloxacin. Patients should be advised to notify their physician if they experience a loss of seizure control or possible symptoms of hydantoin toxicity such as nausea, vomiting, tremors, ataxia, lethargy, slurred speech, visual disturbances, or changes in mental status. Adjustment of hydantoin dosages may be required.

Cipro Iv Minibags

Generic Name: ciprofloxacin

Brand name: Cipro IV, Cipro, Cipro XR, Proquin XR

Synonyms: Cipro I.V. (injection)

What is Cipro Iv Minibags?

Phenytoin

Generic Name: phenytoin

Brand name: Dilantin, Phenytek, Dilantin Infatabs, Phenytoin Sodium, Prompt

Synonyms: n.a.

What is Phenytoin?