Cipro Iv Minibags and Ropivacaine Hydrochloride
Determining the interaction of Cipro Iv Minibags and Ropivacaine Hydrochloride and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Ciprofloxacin may decrease ropivacaine clearance. The proposed mechanism is inhibition of CYP450 1A2-mediated ropivacaine metabolism. The clinical significance is unknown and significant interindividual variation occurs. Clinicians should be aware of the possibility of an interaction if ropivacaine toxicity occurs during concomitant administration.
- Jokinen MJ, Olkkola KT, Ahonen J, Neuvonen PJ "Effect of ciprofloxacin on the pharmacokinetics of ropivacaine." Eur J Clin Pharmacol 58 (2003): 653-7
Generic Name: ciprofloxacin
Brand name: Cipro IV, Cipro, Cipro XR, Proquin XR
Synonyms: Cipro I.V. (injection)
Generic Name: ropivacaine
Brand name: Naropin, Naropin Polyamp, Naropin SDV, Naropin Novaplus
Synonyms: Ropivacaine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cipro Iv Minibags-Ropivacaine Injection
- Cipro Iv Minibags-Rosac
- Cipro Iv Minibags-Rosaclear
- Cipro Iv Minibags-Rosadan
- Cipro Iv Minibags-Rosadan Cream
- Cipro Iv Minibags-Rosadan Cream Kit Topical
- Ropivacaine Hydrochloride-Cipro Tablets
- Ropivacaine Hydrochloride-Cipro XR
- Ropivacaine Hydrochloride-Ciprofloxacin
- Ropivacaine Hydrochloride-Ciprofloxacin (Systemic)
- Ropivacaine Hydrochloride-Ciprofloxacin Extended-Release Tablets
- Ropivacaine Hydrochloride-Ciprofloxacin in 5% Dextrose