Cipro Iv Minibags and Tarceva

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Ciprofloxacin may increase the blood levels of erlotinib. You may need a dose adjustment if you have been taking erlotinib and are starting treatment with ciprofloxacin. Let your doctor know if you experience severe or persistent diarrhea, nausea, vomiting, loss of appetite, skin rash, shortness of breath, cough, or fever while taking these medications, as they may be symptoms caused by increased effects of erlotinib. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Coadministration with an inhibitor of both CYP450 1A2 and 3A4 such as ciprofloxacin may significantly increase the plasma concentrations of erlotinib, which is a substrate of both isoenzymes. According to the product labeling, coadministration with ciprofloxacin increased erlotinib peak plasma concentration (Cmax) and systemic exposure (AUC) by 17% and 39%, respectively, compared to administration of erlotinib alone.

MANAGEMENT: Caution is advised if erlotinib must be used with inhibitors of both CYP450 1A2 and 3A4. A dosage reduction or temporary interruption of therapy should be considered in patients who experience undue adverse effects of erlotinib such as severe diarrhea (i.e., that which is unresponsive to loperamide or results in dehydration), severe skin reactions, or severe liver function test abnormalities.

Cipro Iv Minibags

Generic Name: ciprofloxacin

Brand name: Cipro IV, Cipro, Cipro XR, Proquin XR

Synonyms: Cipro I.V. (injection)

What is Cipro Iv Minibags?

Tarceva

Generic Name: erlotinib

Brand name: Tarceva

Synonyms: n.a.

What is Tarceva?