Drug search by name

Cipro XR and Naropin

Determining the interaction of Cipro XR and Naropin and the possibility of their joint administration.

Check result:

Cipro XR <> Naropin

Relevance: 15.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Ciprofloxacin may decrease ropivacaine clearance. The proposed mechanism is inhibition of CYP450 1A2-mediated ropivacaine metabolism. The clinical significance is unknown and significant interindividual variation occurs. Clinicians should be aware of the possibility of an interaction if ropivacaine toxicity occurs during concomitant administration.

References

Jokinen MJ, Olkkola KT, Ahonen J, Neuvonen PJ "Effect of ciprofloxacin on the pharmacokinetics of ropivacaine." Eur J Clin Pharmacol 58 (2003): 653-7

Cipro XR

Generic Name: ciprofloxacin

Brand name: Cipro, Cipro XR, Proquin XR, Cipro IV

Synonyms: n.a.

What is Cipro XR?

Naropin

Generic Name: ropivacaine

Brand name: Naropin, Naropin Polyamp, Naropin SDV, Naropin Novaplus

Synonyms: n.a.

What is Naropin?

+ Add a drug Remove all

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

The list of popular interactions