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Cipro XR and Reglan (Metoclopramide Injection Solution)

Determining the interaction of Cipro XR and Reglan (Metoclopramide Injection Solution) and the possibility of their joint administration.

Check result:
Cipro XR <> Reglan (Metoclopramide Injection Solution)
Relevance: 15.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Metoclopramide increases the rate of absorption of oral ciprofloxacin, resulting in a shorter time to reach maximum plasma concentrations. The bioavailability is not affected. The probable mechanism is increased gastric motility by metoclopramide. The clinical significance are unknown.

References
  • "Product Information. Cipro (ciprofloxacin)." Bayer, West Haven, CT.
Cipro XR

Generic Name: ciprofloxacin

Brand name: Cipro, Cipro XR, Proquin XR, Cipro IV

Synonyms: n.a.

Reglan (Metoclopramide Injection Solution)

Generic Name: metoclopramide

Brand name: Reglan, Metozolv ODT

Synonyms: Reglan

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.