Cipro XR and Zyprexa Intramuscular

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Ciprofloxacin may increase olanzapine plasma concentrations. The proposed mechanism is inhibition of hepatic CYP450 1A2 which is partially responsible for the metabolism of olanzapine. A case report noted a doubling of the olanzapine plasma concentration following administration of ciprofloxacin. No adverse effects were observed. Correlation between increased olanzapine plasma concentrations and side effects or response has not been determined. Other fluoroquinolones with a similar metabolic profile may also affect olanzapine. Clinical monitoring of patient tolerance and response, including laboratory olanzapine serum concentrations, is recommended.

Cipro XR

Generic Name: ciprofloxacin

Brand name: Cipro, Cipro XR, Proquin XR, Cipro IV

Synonyms: n.a.

What is Cipro XR?

Zyprexa Intramuscular

Generic Name: olanzapine

Brand name: Zyprexa Intramuscular, Zyprexa, Zyprexa Zydis, Zyprexa Relprevv

Synonyms: n.a.

What is Zyprexa Intramuscular?