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Cisapride Suspension and Diazepam Tablet

Determining the interaction of Cisapride Suspension and Diazepam Tablet and the possibility of their joint administration.

Check result:

Cisapride Suspension <> Diazepam Tablet

Relevance: 02.09.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Cisapride is no longer on the market in the US. Do not take cisapride with any other medication.

Professional:

MONITOR: Cisapride may increase the rate but not the extent of diazepam absorption. In one study, coadministration of cisapride significantly increased impairment of reaction time in the first 45 minutes after diazepam administration.

MANAGEMENT: It is recommended that patients be monitored for excessive CNS depression during concomitant therapy. Patients should be advised to report prolonged or excessive sedation to their physician.

References

Greiff JMC, Rowbotham D "Pharmacokinetic drug interactions with gastrointestinal motility modifying agents." Clin Pharmacokinet 27 (1994): 447-61

Cisapride Suspension

Generic Name: cisapride

Brand name: Propulsid

Synonyms: Cisapride Tablets

What is Cisapride Suspension?

Diazepam Tablet

Generic Name: diazepam

Brand name: Valium, Diastat, Diastat AcuDial, Diastat Pediatric, Diazepam Intensol, Zetran

Synonyms: Diazepam

What is Diazepam Tablet?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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