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Cisapride Suspension and Hyoscyamine Orally Disintegrating Tablets

Determining the interaction of Cisapride Suspension and Hyoscyamine Orally Disintegrating Tablets and the possibility of their joint administration.

Check result:
Cisapride Suspension <> Hyoscyamine Orally Disintegrating Tablets
Relevance: 02.09.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Cisapride in no longer on the market in the US. Do not take cisapride with any other medication.

Professional:

GENERALLY AVOID: Concomitant administration of anticholinergic agents would be expected to compromise the beneficial effects of cisapride. Cisapride enhances the release of acetylcholine to produce increased gastrointestinal motility. Anticholinergic agents by blocking this action could delay gastric emptying and worsen esophageal reflux.

MANAGEMENT: This combination should be avoided.

References
  • "Product Information. Propulsid (cisapride)." Janssen Pharmaceutica, Titusville, NJ.
Cisapride Suspension

Generic Name: cisapride

Brand name: Propulsid

Synonyms: Cisapride Tablets

Hyoscyamine Orally Disintegrating Tablets

Generic Name: hyoscyamine

Brand name: Anaspaz, Ed Spaz, Hyosyne, Levbid, Levsin, NuLev, Symax SR, Cystospaz, Levsin SL, Cystospaz-M, Levsinex SR, Symax SL, A-Spas S/L, Donnamar, Hyosol, NuLev, Spasdel, IB-Stat, Hyospaz, Symax Duotab, Symax FasTab, HyoMax SL, HyoMax SR, HyoMax FT, HyoMax DT, HyoMax, Oscimin, A-Spaz, Levsin/SL, Colidrops, Levsinex, Symax, Symax FasTabs

Synonyms: Hyoscyamine

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.