Cisapride Tablets and Diazepam Rectal Gel
Determining the interaction of Cisapride Tablets and Diazepam Rectal Gel and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Cisapride is no longer on the market in the US. Do not take cisapride with any other medication.
Professional:MONITOR: Cisapride may increase the rate but not the extent of diazepam absorption. In one study, coadministration of cisapride significantly increased impairment of reaction time in the first 45 minutes after diazepam administration.
MANAGEMENT: It is recommended that patients be monitored for excessive CNS depression during concomitant therapy. Patients should be advised to report prolonged or excessive sedation to their physician.
- Greiff JMC, Rowbotham D "Pharmacokinetic drug interactions with gastrointestinal motility modifying agents." Clin Pharmacokinet 27 (1994): 447-61
Generic Name: cisapride
Brand name: Propulsid
Synonyms: n.a.
Generic Name: diazepam
Brand name: Valium, Diastat, Diastat AcuDial, Diastat Pediatric, Diazepam Intensol, Zetran
Synonyms: Diazepam
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cisapride Tablets-Diazepam Solution
- Cisapride Tablets-Diazepam Tablet
- Cisapride Tablets-Diazepam Tablets
- Cisapride Tablets-Diazoxide
- Cisapride Tablets-Diazoxide Capsules
- Cisapride Tablets-Diazoxide Suspension
- Diazepam Rectal Gel-Cisatracurium
- Diazepam Rectal Gel-Cisatracurium Besylate
- Diazepam Rectal Gel-Cisatracurium Besylate Injection
- Diazepam Rectal Gel-Cisatracurium besylate Intravenous
- Diazepam Rectal Gel-Cisplatin
- Diazepam Rectal Gel-Cisplatin Intravenous