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Cisatracurium and Lazanda

Determining the interaction of Cisatracurium and Lazanda and the possibility of their joint administration.

Check result:

Cisatracurium <> Lazanda

Relevance: 03.05.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using fentaNYL together with cisatracurium during surgery may increase the risk of cardiovascular side effects such as irregular heart beat or low blood pressure. You will need to be closely monitored by your doctor and/or anesthesiologist to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Alfentanil or fentanyl, when combined with neuromuscular blocking agents during surgical procedures, may adversely affect cardiovascular function. Tachycardia, bradycardia, and/or hypotension may result.

MANAGEMENT: The patient should be monitored closely for altered hemodynamics.

References

"Product Information. Alfenta (alfentanil)." Janssen Pharmaceutica, Titusville, NJ.
Taylor B, MacEwen P "Asystole after alfentanil-succinylcholine." Can J Anaesth 36 (1989): 255-6
Reid C, Crosby E, Reid D "Sinus arrest following administration of alfentanil." Can J Anaesth 38 (1991): 540-1

Cisatracurium

Generic Name: cisatracurium

Brand name: Nimbex

Synonyms: n.a.

What is Cisatracurium?

Lazanda

Generic Name: fentanyl

Brand name: Lazanda, Abstral, Fentora, Subsys, Actiq, Duragesic, Ionsys, Onsolis, Sublimaze

Synonyms: Lazanda Nasal Spray

What is Lazanda?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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