Cisatracurium Besylate Injection and Polymyxin B

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Ask your doctor before using cisatracurium together with polymyxin B sulfate. Using these medications together may cause serious breathing problems. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: Polymyxin B may prolong apnea and respiratory paralysis after use of neuromuscular blocking agents. The mechanism may be related to decreased intracellular potassium or decreased ionized serum calcium. Intravenous calcium administration may be helpful in reversing the paralysis.

MANAGEMENT: This combination should be avoided unless the benefit outweighs the risk. Patients should be closely monitored for signs of extended neuromuscular blockade.

Cisatracurium Besylate Injection

Generic Name: cisatracurium

Brand name: Nimbex

Synonyms: Cisatracurium

What is Cisatracurium Besylate Injection?

Polymyxin B

Generic Name: polymyxin b

Brand name: Poly-Rx

Synonyms: n.a.

What is Polymyxin B?