Cisplatin and Vitamin C
Determining the interaction of Cisplatin and Vitamin C and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:One study found that ascorbic acid can improve the antineoplastic activity of doxorubicin, cisplatin, and paclitaxel in human breast carcinoma cells in vitro. The clinical significance of this finding is not known.
- Kurbacher CM, Wagner U, Kolster B, Andreotti PE, Krebs D, Bruckner HW "Ascorbic acid (vitamin c) improves the antineoplastic activity of doxorubicin, cisplatin, and paclitaxel in human breast carcinoma cells in vitro." Cancer Lett 103 (1996): 183-9
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: cisplatin
Brand name: Platinol, Platinol-AQ
Synonyms: CISplatin
Generic Name: ascorbic acid
Brand name: Acerola, Ascorbic Acid Quick Melts, C/Rose Hips, Cecon, Cemill 500, C-Time, Ester-C, N Ice with Vitamin C, Sunkist Vitamin C, Vasoflex HD, Vicks Vitamin C Drops, Vitamin C, Cenolate, Mega-C-Acid Plus, Cee-500, C-500-Gr, Centrum Singles-Vitamin C, Ascot, Cevi-Bid, Vitamin C TR, Vitamin C with Rose Hips, Cemill 1000, Ascor L NC, Ascor, Ascor L 500, Betac, Cemill, Protexin
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cisplatin-Vitamin C Powder
- Cisplatin-Vitamin D
- Cisplatin-Vitamin D Ergocalciferol
- Cisplatin-Vitamin D2
- Cisplatin-Vitamin D3
- Cisplatin-Vitamin Deficiency System
- Vitamin C-Cisplatin Intravenous
- Vitamin C-Citalopram
- Vitamin C-Citalopram Capsules
- Vitamin C-Citalopram Hydrobromide
- Vitamin C-Citalopram Oral Solution
- Vitamin C-Citalopram Solution
Cisplatin - Vitamin C 
Cisplatin - Vitamin C 
Cisplatin - Vitamin C 
Cisplatin - Vitamin C 
Cisplatin - Vitamin C 
Cisplatin - Vitamin C 
Cisplatin - Vitamin C 
Cisplatin - Vitamin C 
Cisplatin - Vitamin C 
Cisplatin - Vitamin C 
Cisplatin - Vitamin C 
Cisplatin - Vitamin C