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Citalopram Hydrobromide and Cogentin

Determining the interaction of Citalopram Hydrobromide and Cogentin and the possibility of their joint administration.

Check result:

Citalopram Hydrobromide <> Cogentin

Relevance: 22.07.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using benztropine together with medications like citalopram has been associated with extremely rare reports of delirium. Let your doctor know if you experience confusion, disordered speech, unusual thoughts or behavior, or hallucinations during treatment with these medications. Avoid driving or operating hazardous machinery until you know how the medications affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Delirium has been observed during the coadministration of benztropine and selective serotonin reuptake inhibitors (SSRIs). The mechanism of this potential interaction, if any, has not been determined. There have only been isolated case reports, and concomitant neuroleptic use was common.

MANAGEMENT: Until further data are available, it may be appropriate to monitor patients for evidence of delirium or other unusual psychiatric reactions when benztropine is given with SSRIs, especially if neuroleptic therapy is also administered.

References

Roth A, Akyol S, Nelson JC "Delirium associated with the combination of a neuroleptic, an SSRI, and benztropine." J Clin Psychiatry 55 (1994): 492-5
Armstrong SC, Schweitzer SM "Delirium associated with paroxetine and benztropine combination." Am J Psychiatry 154 (1997): 581-2
Byerly MJ, Christensen RC, Evans DL "Delirium associated with a combination of sertraline, haloperidol, and benztropine." Am J Psychiatry 153 (1996): 965-6

Citalopram Hydrobromide

Generic Name: citalopram

Brand name: Celexa

Synonyms: Citalopram

What is Citalopram Hydrobromide?

Cogentin

Generic Name: benztropine

Brand name: Cogentin

Synonyms: n.a.

What is Cogentin?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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