Citalopram Hydrobromide and Icatibant

• Generic Name: citalopram
• Dosage Forms: n.a.
• Other Brand Names: Celexa

Management of major depressive disorder.

Manufacturers state efficacy in hospital settings not established. However, efficacy has been demonstrated in hospitalized patients with depression, including severe depression, in several studies.

APA states that effectiveness of antidepressants is generally comparable between and within classes of medications, including SSRIs, SNRIs, TCAs, MAO inhibitors, and other antidepressants (e.g., bupropion, mirtazapine, trazodone). Choose antidepressant based mainly on the following factors: patient preference; nature of prior response to medication; safety, tolerability, and anticipated adverse effects; concurrent psychiatric and medical conditions; specific properties of the medication (e.g., half-life, actions on CYP isoenzymes, other drug interactions); and cost. For most patients, an SSRI, SNRI, mirtazapine, or bupropion is considered optimal. Consult APA’s Practice Guidelines for the Treatment of Patients with Major Depressive Disorder for additional information.

Has been used in the management of obsessive-compulsive disorder.

Has been used in the management of panic disorder with or without agoraphobia.

Has been used in the management of social phobia (social anxiety disorder).

Has been used in the management of alcohol dependence.

Has been used in the management of premenstrual dysphoric disorder (previously late luteal phase dysphoric disorder).

Has been used for the management of premature ejaculation.

May be less effective than some other SSRIs (e.g., paroxetine).

Has been used in the management of bulimia nervosa or anorexia nervosa with equivocal efficacy.

Has been used in the management of diabetic neuropathy.

Has been used in a limited number of adults with civilian- or combat-related posttraumatic stress disorder (PTSD).

• Generic Name: icatibant
• Dosage Forms: n.a.
• Other Brand Names: Firazyr

Icatibant is used to treat attacks of hereditary angioedema (an immune system disorder) in adults.

Icatibant is not a cure for hereditary angioedema.

Icatibant may also be used for purposes not listed in this medication guide.