Citric Acid, Sodium Citrate, and Potassium Citrate and Kristalose
Determining the interaction of Citric Acid, Sodium Citrate, and Potassium Citrate and Kristalose and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Preliminary data from studies in humans and rats suggest that nonabsorbable antacids given concurrently with lactulose may inhibit the reduction in colonic pH induced by lactulose. Theoretically, this may reduce the effectiveness of lactulose in the treatment of portal-systemic encephalopathy, which requires an acidic environment in the colon to promote extraction of ammonia from the blood as well as retention/elimination of ammonia as the ammonium ion. However, the clinical relevance of this interaction has not been fully elucidated.
- "Product Information. Cephulac (lactulose)." Hoechst Marion-Roussel Inc, Kansas City, MO.
- "Product Information. Chronulac (lactulose)." Hoechst Marion-Roussel Inc, Kansas City, MO.
Generic Name: citric acid / potassium citrate / sodium citrate
Brand name: Cytra-3, Polycitra, Polycitra-LC, Tricitrates, Virtrate-3
Synonyms: Citric acid, potassium citrate, and sodium citrate
Generic Name: lactulose
Brand name: Constulose, Kristalose, Duphalac, Enulose, Generlac, Chronulac, Cephulac, Constilac, Cholac, Evalose, Heptalac
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Citric Acid, Sodium Citrate, and Potassium Citrate-Kruschen Salts
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- Citric Acid, Sodium Citrate, and Potassium Citrate-Kurvelo
- Citric Acid, Sodium Citrate, and Potassium Citrate-Kuvan
- Citric Acid, Sodium Citrate, and Potassium Citrate-Kuvan (Sapropterin Powder for Oral Solution)
- Citric Acid, Sodium Citrate, and Potassium Citrate-Kuvan (Sapropterin Tablets)
- Kristalose-Citroma
- Kristalose-Citrucel
- Kristalose-Citrucel (Methylcellulose Powder and Powder Packets)
- Kristalose-Citrucel (Methylcellulose Tablets)
- Kristalose-Citrucel Tablets
- Kristalose-Cladribine