Cladribine and Epivir HBV
Determining the interaction of Cladribine and Epivir HBV and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Talk to your doctor before using cladribine together with lamiVUDine. Some investigators have suggested that medications like lamiVUDine may reduce the effectiveness of cladribine, although this has not been studied extensively. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: The use of cladribine with medications that undergo intracellular phosphorylation may reduce its efficacy by inhibiting its phosphorylation to its active form. The clinical significance of this interaction is unknown.
MANAGEMENT: Concomitant use of cladribine with medications that undergo intracellular phosphorylation should be avoided if possible.
- EMEA. European Medicines Agency "EPARs. European Union Public Assessment Reports. Available from: URL: http://www.ema.europa.eu/ema/index.jsp?curl=pages/includes/medicines/medicines_landingpage.jsp&mid."
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Leustatin (cladribine)." Ortho Biotech Inc, Raritan, NJ.
Generic Name: cladribine
Brand name: Mavenclad, Leustatin
Synonyms: n.a.
Generic Name: lamivudine
Brand name: Epivir, Epivir HBV
Synonyms: Epivir-HBV
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cladribine-Epivir-HBV (Lamivudine Oral Solution)
- Cladribine-Epivir-HBV (Lamivudine Tablets)
- Cladribine-Eplerenone
- Cladribine-Epoetin alfa
- Cladribine-Epoetin alfa Injection
- Cladribine-Epoetin Alfa Vials
- Epivir HBV-Cladribine (oral)
- Epivir HBV-Cladribine injection
- Epivir HBV-Cladribine Intravenous
- Epivir HBV-Cladribine Tablets
- Epivir HBV-Claforan
- Epivir HBV-Claforan in D5W