Cladribine Tablets and Didanosine Tablet, for suspension
Determining the interaction of Cladribine Tablets and Didanosine Tablet, for suspension and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Talk to your doctor before using cladribine together with didanosine. Some investigators have suggested that medications like didanosine may reduce the effectiveness of cladribine, although this has not been studied extensively. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: The use of cladribine with medications that undergo intracellular phosphorylation may reduce its efficacy by inhibiting its phosphorylation to its active form. The clinical significance of this interaction is unknown.
MANAGEMENT: Concomitant use of cladribine with medications that undergo intracellular phosphorylation should be avoided if possible.
- EMEA. European Medicines Agency "EPARs. European Union Public Assessment Reports. Available from: URL: http://www.ema.europa.eu/ema/index.jsp?curl=pages/includes/medicines/medicines_landingpage.jsp&mid."
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Leustatin (cladribine)." Ortho Biotech Inc, Raritan, NJ.
Generic Name: cladribine
Brand name: Mavenclad, Leustatin
Synonyms: Cladribine
Generic Name: didanosine
Brand name: Videx, Videx EC
Synonyms: Didanosine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cladribine Tablets-Didrex
- Cladribine Tablets-Didronel
- Cladribine Tablets-Dienogest and estradiol
- Cladribine Tablets-Diethylene Triamine Penta-Acetic Acid
- Cladribine Tablets-Diethylpropion
- Cladribine Tablets-Diethylpropion Controlled-Release Tablets
- Didanosine Tablet, for suspension-Claforan
- Didanosine Tablet, for suspension-Claforan in D5W
- Didanosine Tablet, for suspension-Claravis
- Didanosine Tablet, for suspension-Clarifoam EF
- Didanosine Tablet, for suspension-Clarinex
- Didanosine Tablet, for suspension-Clarinex (Desloratadine Syrup)