Claravis and Vitamin A

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using vitamin A together with ISOtretinoin is generally not recommended. Combining these medications may increase the risk of hypervitaminosis A, a condition that stems from excessive vitamin A-related effects. Potentially serious problems that could occur include vision impairment, increased pressure in the brain, high cholesterol/triglycerides, and inflammation of the liver, pancreas, or the rest of the digestive tract. Check your food and medicine labels to make sure you do not consume additional vitamin A in excess of the recommended daily allowance. Talk to your doctor or pharmacist if you are uncertain whether you are getting too much vitamin A. Early signs and symptoms of hypervitaminosis A include inflammation or bleeding of the gums or lips; dry, scaly, itchy, or red skin; hair loss; headache; dizziness; and nausea. You should seek immediate medical attention if you experience potential signs that could indicate increased pressure in the brain (headache, nausea, vomiting, visual disturbances) or liver damage (fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, yellowing of the skin or eyes). It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: Concomitant use of a retinoid with vitamin A or other retinoids may result in hypervitaminosis A and additive toxicities. Patients may be at increased risk for potentially serious adverse effects such as vision impairment, pseudotumor cerebri (benign intracranial hypertension), mucositis, esophagitis, hepatitis, hypertriglyceridemia, pancreatitis, ileitis, and colitis.

MANAGEMENT: Patients receiving retinoid therapy should avoid concurrent use of other retinoids or vitamin A supplements in excess of the recommended daily allowance. Patients should be made aware of vitamin A sources in vitamin supplements, fortified foods and over-the-counter medications, and be advised to contact their physician if they experience signs of hypervitaminosis A such as inflammation or bleeding of the gums or lips; dry, scaly skin; alopecia; pruritus; erythema; headache; vertigo; and nausea. Patients should discontinue the medication and seek immediate medical attention if they develop signs and symptoms of pseudotumour cerebri (e.g., headache, nausea, vomiting, visual disturbances, papilledema) or hepatotoxicity (e.g., fever, rash, anorexia, nausea, vomiting, fatigue, right upper quadrant pain, dark urine, jaundice).

Claravis

Generic Name: isotretinoin

Brand name: Absorica, Amnesteem, Claravis, Myorisan, Sotret, Zenatane, Accutane

Synonyms: n.a.

What is Claravis?

Vitamin A

Generic Name: vitamin a

Brand name: Aquasol A, A-25, A/Fish Oil, Vitamin A Fish

Synonyms: n.a.

What is Vitamin A?