Cleocin (Clindamycin Capsules) and Erythromycin Delayed-Release Tablet
Determining the interaction of Cleocin (Clindamycin Capsules) and Erythromycin Delayed-Release Tablet and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Ask your doctor before using clindamycin together with erythromycin. Using these medications together may cause either drug to be less effective. Contact your doctor immediately if your infection worsens. You may need a dose adjustment if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Lincomycin derivatives and erythromycin have antagonistic effects in vitro. The mechanism is competitive binding of the 50S ribosomal subunit.
MANAGEMENT: Clindamycin or lincomycin should not be used concurrently with erythromycin.
- Hardman JG, Gilman AG, Limbird LE eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 9th ed." New York, NY: McGraw-Hill (1995):
- "Product Information. Cleocin (clindamycin)." Pharmacia and Upjohn, Kalamazoo, MI.
Generic Name: clindamycin
Brand name: Cleocin, Cleocin Pediatric, Cleocin HCl, Cleocin Phosphate, Cleocin Phosphate ADD-Vantage, Clindesse, ClindaMax Vaginal
Synonyms: Cleocin
Generic Name: erythromycin
Brand name: EES. Granules, EES-400 Filmtab, EryPed 200, EryPed 400, Ery-Tab, Erythrocin Lactobionate, Erythrocin Stearate Filmtab, PCE Dispertab, E. E. S, EryPed, Erythrocin, Erythromycin Filmtabs, Erythromycin Lactobionate - IV
Synonyms: Erythromycin, Erythromycin (Systemic)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cleocin (Clindamycin Capsules)-Erythromycin Delayed-Release Tablets and Capsules
- Cleocin (Clindamycin Capsules)-Erythromycin Ethyl Succinate Tablets
- Cleocin (Clindamycin Capsules)-Erythromycin Filmtabs
- Cleocin (Clindamycin Capsules)-Erythromycin Injection
- Cleocin (Clindamycin Capsules)-Erythromycin Intravenous
- Cleocin (Clindamycin Capsules)-Erythromycin Lactobionate - I.V.
- Erythromycin Delayed-Release Tablet-Cleocin (Clindamycin Injection)
- Erythromycin Delayed-Release Tablet-Cleocin (Clindamycin Vaginal Cream)
- Erythromycin Delayed-Release Tablet-Cleocin (Clindamycin Vaginal Suppositories)
- Erythromycin Delayed-Release Tablet-Cleocin HCl Oral
- Erythromycin Delayed-Release Tablet-Cleocin Pediatric
- Erythromycin Delayed-Release Tablet-Cleocin Pediatric Oral