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Cleocin Pediatric Oral and Totacillin-N injection

Determining the interaction of Cleocin Pediatric Oral and Totacillin-N injection and the possibility of their joint administration.

Check result:

Cleocin Pediatric Oral <> Totacillin-N injection

Relevance: 21.09.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

The combination of clindamycin and ampicillin may result in a higher incidence of diarrhea than with either drug alone. The mechanism may be related to additive effects on the gut microflora.

References

Brause BD, Romankiewicz JA, Gotz V, Franklin JE Jr, Roberts RB "Comparative study of diarrhea associated with clindamycin and ampicillin therapy." Am J Gastroenterol 73 (1980): 244-8

Cleocin Pediatric Oral

Generic Name: clindamycin

Brand name: Cleocin Pediatric, Cleocin, Cleocin HCl, Cleocin Phosphate, Cleocin Phosphate ADD-Vantage, Clindesse, ClindaMax Vaginal

Synonyms: Cleocin Pediatric

What is Cleocin Pediatric Oral?

Totacillin-N injection

Generic Name: ampicillin

Brand name: Omnipen-N, Totacillin-N, Principen, Ampicillin

Synonyms: Totacillin-N (injection)

What is Totacillin-N injection?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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