Clevidipine Butyrate and Hyzaar

• Generic Name: clevidipine
• Dosage Forms: n.a.
• Other Brand Names: Cleviprex

Used to reduce BP when oral antihypertensive therapy not feasible or desirable.

Calcium-channel blockers considered one of several preferred antihypertensive drug classes for initial management of hypertension; other preferred options include ACE inhibitors, angiotensin II receptor antagonists, and thiazide diuretics.

Clevidipine used for management of perioperative hypertension (e.g., in cardiac surgery), essential hypertension, and severe hypertension (e.g., hypertensive emergencies).

Some experts state that clevidipine is one of the preferred agents for the management of hypertensive emergencies in patients with certain comorbidities such as acute pulmonary edema, acute renal failure, and acute sympathetic discharge or catecholamine excess states (e.g., pheochromocytoma, post-carotid endarterectomy status). (See Pheochromocytoma under Cautions.)

• Generic Name: hydrochlorothiazide / losartan
• Dosage Forms: tablet, film coated
• Other Brand Names: Hyzaar

Hyzaar contains a combination of hydrochlorothiazide and losartan. Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Losartan is an angiotensin II receptor antagonist (sometimes called an ARB blocker). Losartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

Hyzaar is used to treat high blood pressure (hypertension).

Hyzaar is also used to lower the risk of stroke in certain people with heart disease.