Clevidipine Butyrate and Rozlytrek

• Generic Name: clevidipine
• Dosage Forms: n.a.
• Other Brand Names: Cleviprex

Used to reduce BP when oral antihypertensive therapy not feasible or desirable.

Calcium-channel blockers considered one of several preferred antihypertensive drug classes for initial management of hypertension; other preferred options include ACE inhibitors, angiotensin II receptor antagonists, and thiazide diuretics.

Clevidipine used for management of perioperative hypertension (e.g., in cardiac surgery), essential hypertension, and severe hypertension (e.g., hypertensive emergencies).

Some experts state that clevidipine is one of the preferred agents for the management of hypertensive emergencies in patients with certain comorbidities such as acute pulmonary edema, acute renal failure, and acute sympathetic discharge or catecholamine excess states (e.g., pheochromocytoma, post-carotid endarterectomy status). (See Pheochromocytoma under Cautions.)

• Generic Name: entrectinib
• Dosage Forms: capsule
• Other Brand Names: Rozlytrek

Rozlytrek (entrectinib) is used in adults to treat non-small cell lung cancer that has spread to other parts of the body (metastatic).

Rozlytrek is also used in adults and children at least 12 years old who have solid tumors that have spread or cannot be safely removed with surgery, or when other treatments have failed or are not safe options.

Rozlytrek is used only if your cancer has a specific abnormal gene. Your doctor will test you for this gene.