Clidinium and Chlordiazepoxide and Formerly available as Librium

• Generic Name: chlordiazepoxide / clidinium
• Dosage Forms: capsule, gelatin coated
• Other Brand Names: Librax, Clindex, Chlordinium

• It is used to treat irritable bowel syndrome.
• It is used to treat ulcer disease.
• It is used to treat certain types of bowel inflammation.

• Generic Name: chlordiazepoxide
• Dosage Forms: n.a.
• Other Brand Names: Formerly available as Librium, Librium, Libritabs, Poxi, Mitran

Relief of agitation and tremor and prevention or symptomatic relief of delirium tremens and hallucinations associated with acute alcohol withdrawal.

Management of anxiety disorders and short-term relief of symptoms of anxiety.

Management of moderate to severe anxiety (in fixed-combination with amitriptyline hydrochloride) in patients with moderate to severe depression.

Preoperatively to relieve anxiety.

Has been used in fixed combination with clidinium bromide as an adjunct in the treatment of peptic ulcer disease, functional disturbances of GI motility (e.g., irritable bowel syndrome), and acute enterocolitis. Fixed combination is classified by FDA as possibly effective for these indications.

Has limited usefulness in the treatment of peptic ulcer disease because of the advent of more effective therapies for this condition.

Therapeutic benefits achieved with the combination preparation in the management of functional disturbances of GI motility may be attributed to the anxiolytic and/or sedative properties of chlordiazepoxide.

Although the fixed combination has been used in the treatment of acute enterocolitis, antimuscarinic-containing preparations should be used with extreme caution in patients with diarrhea or ulcerative colitis.