Climara Pro and Fentanyl Lozenge
Determining the interaction of Climara Pro and Fentanyl Lozenge and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Coadministration of fentanyl with other drugs, such as estrogens, that are also metabolized by CYP450 may theoretically result in elevated plasma concentrations of fentanyl and/or the coadministered drug(s). The mechanism is decreased drug clearance due to competitive inhibition of CYP450 activity. Although clinical data are lacking, the possibility of prolonged and/or increased pharmacologic effects of the drugs should be considered.
- Cerner Multum, Inc. "Australian Product Information." O 0
Generic Name: estradiol / levonorgestrel
Brand name: Climara Pro
Synonyms: n.a.
Generic Name: fentanyl
Brand name: Duragesic, Abstral, Fentora, Subsys, Actiq, Ionsys, Lazanda, Onsolis, Sublimaze
Synonyms: Fentanyl Patch, FentaNYL
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Climara Pro-Fentanyl nasal
- Climara Pro-Fentanyl Nasal Spray
- Climara Pro-Fentanyl Novaplus Patch
- Climara Pro-Fentanyl Sublingual Spray
- Climara Pro-Fentanyl Sublingual Tablet
- Climara Pro-Fentanyl Transdermal
- Fentanyl Lozenge-Climara Pro transdermal
- Fentanyl Lozenge-Climara Transdermal
- Fentanyl Lozenge-CLIN Single Use Kit
- Fentanyl Lozenge-Clinac BPO 7
- Fentanyl Lozenge-Clinacort
- Fentanyl Lozenge-Clinda-Derm