Climara Pro and Imbruvica

• Generic Name: estradiol / levonorgestrel
• Dosage Forms: patch
• Other Brand Names: Climara Pro

Climara Pro is a skin patch containg estradiol and levonorgestrel. Estradiol is a form of estrogen, a female sex hormone that regulates many processes in the body. Levonorgestrel is a form of progesterone, a female hormone important for regulating ovulation and menstruation.

Climara Pro is used to treat menopause symptoms such as hot flashes, and to prevent osteoporosis (bone loss) in menopausal women.

Climara Pro may also be used for purposes other than those listed here.

• Generic Name: ibrutinib
• Dosage Forms: capsule
• Other Brand Names: Imbruvica

Imbruvica (ibrutinib) is a cancer medicine that interferes with the growth and spread of cancer cells in the body.

Imbruvica is used to treat mantle cell lymphoma, marginal zone lymphoma, Waldenstrom's macroglobulinemia, chronic lymphocytic leukemia, and small lymphocytic lymphoma. This medicine is also used to treat chronic graft-versus-host disease.

Imbruvica is usually given after other treatments have have not been effective.

Imbruvica was approved to treat mantle cell and marginal lymphomas by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to this medicine, but further studies are needed.