Clindamycin Palmitate Hydrochloride Granules and PCE Dispertab
Determining the interaction of Clindamycin Palmitate Hydrochloride Granules and PCE Dispertab and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Ask your doctor before using clindamycin together with erythromycin. Using these medications together may cause either drug to be less effective. Contact your doctor immediately if your infection worsens. You may need a dose adjustment if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Lincomycin derivatives and erythromycin have antagonistic effects in vitro. The mechanism is competitive binding of the 50S ribosomal subunit.
MANAGEMENT: Clindamycin or lincomycin should not be used concurrently with erythromycin.
- Hardman JG, Gilman AG, Limbird LE eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 9th ed." New York, NY: McGraw-Hill (1995):
- "Product Information. Cleocin (clindamycin)." Pharmacia and Upjohn, Kalamazoo, MI.
Generic Name: clindamycin
Brand name: Cleocin HCl, Cleocin Pediatric, Cleocin Phosphate, Cleocin Phosphate ADD-Vantage, Clindesse, ClindaMax Vaginal, Cleocin
Synonyms: Clindamycin, Clindamycin (Systemic)
Generic Name: erythromycin
Brand name: EES. Granules, EES-400 Filmtab, EryPed 200, EryPed 400, Ery-Tab, Erythrocin Lactobionate, Erythrocin Stearate Filmtab, PCE Dispertab, E. E. S, EryPed, Erythrocin, Erythromycin Filmtabs, Erythromycin Lactobionate - IV
Synonyms: PCE Dispertab (Oral), PCE, PCE (Oral)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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