Clindamycin Phosphate topical and Coumadin Injection

• Generic Name: clindamycin topical
• Dosage Forms: n.a.
• Other Brand Names: Cleocin T, Clindacin ETZ, Clindacin P, Clindagel, Clindamax, Evoclin, Cleocin, Clindesse, Clindamax, Clindesse Cream, Clindets, ClindaReach Pledget

Treatment of inflammatory acne vulgaris; used alone or in conjunction with benzoyl peroxide.

Generally effective for treatment of mild to moderate inflammatory acne.

May induce bacterial resistance when used as monotherapy; resistance associated with decreased clinical efficacy.

Particularly useful when used in combination with benzoyl peroxide or topical retinoids; reduction in total lesion count of 50–70% reported when combination therapy used.

Treatment of bacterial vaginosis (formerly called Haemophilus vaginitis, Gardnerella vaginitis, nonspecific vaginitis, Corynebacterium vaginitis, or anaerobic vaginosis).

CDC recommends treatment of bacterial vaginosis in all symptomatic women (including pregnant women). In addition, asymptomatic pregnant women at high risk for complications of pregnancy should be screened (preferably at the first prenatal visit) and treatment initiated if needed.

Treatment recommendations for bacterial vaginosis in HIV-infected women are the same as those for women without HIV infection.

Regimens of choice in nonpregnant women are a 7-day regimen of oral metronidazole; a 5-day regimen of intravaginal metronidazole gel; or a 7-day regimen of intravaginal clindamycin cream; alternative regimens are a 7-day regimen of oral clindamycin or 3-day regimen of intravaginal clindamycin suppositories. The preferred regimens for pregnant women are a 7-day regimen of oral metronidazole or oral clindamycin.

Regardless of regimen used, relapse or recurrence is common; an alternative regimen (e.g., oral therapy when topical was used initially) may be used in such situations.

Routine treatment of asymptomatic male sexual contacts of women who have relapsing or recurrent bacterial vaginosis not recommended.

• Generic Name: warfarin
• Dosage Forms: tablet, injection, powder, lyophilized, for solution
• Other Brand Names: Coumadin, Jantoven

Coumadin (warfarin) is an anticoagulant (blood thinner). Warfarin reduces the formation of blood clots.

Coumadin is used to treat or prevent blood clots in veins or arteries, which can reduce the risk of stroke, heart attack, or other serious conditions.

Coumadin may also be used for purposes not listed in this medication guide.