Clindamycin (Systemic) and Verelan PM

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Before taking clindamycin, tell your doctor if you also use verapamil. You may need dose adjustments or special tests in order to safely take both medications together. Taking these medications together may increase the effects of verapamil. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor first.

MONITOR: According to a single case report, when ceftriaxone and clindamycin were added to the regimen of a patient who was receiving a stable dosage of verapamil and other medications, acute verapamil toxicity resulted. The patient developed complete heart block. The mechanism is unknown and causality was not clearly determined. The purported mechanism (displacement of verapamil from protein binding sites) has been disputed.

MANAGEMENT: Until more information is available, patients should be monitored for verapamil toxicity.

Clindamycin (Systemic)

Generic Name: clindamycin

Brand name: Cleocin HCl, Cleocin Pediatric, Cleocin Phosphate, Cleocin Phosphate ADD-Vantage, Clindesse, ClindaMax Vaginal, Cleocin

Synonyms: Clindamycin

What is Clindamycin (Systemic)?

Verelan PM

Generic Name: verapamil

Brand name: Verelan PM, Calan, Calan SR, Isoptin SR, Verelan, Isoptin, Isoptin IV, Covera-HS

Synonyms: n.a.

What is Verelan PM?