Clofibrate and Furosemide Oral Solution
Determining the interaction of Clofibrate and Furosemide Oral Solution and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Clofibrate may increase the diuretic effect of furosemide by displacing it from its protein-binding sites. A reduction in furosemide dosage may be required, especially in patients with the nephrotic syndrome who have reduced albumin levels. If clofibrate and furosemide are used together, the patient should be monitored more closely for electrolyte imbalances.
- "Product Information. Atromid-S (clofibrate)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
- Bridgman JF, Rosen SM, Thorp JM "Complications during clofibrate treatment of nephrotic-syndrome hyperlipoproteinaemia." Lancet 2 (1972): 506-9
- Prandota J, Pruitt AW "Furosemide binding to human albumin and plasma of nephrotic children." Clin Pharmacol Ther 17 (1975): 159-66
Generic Name: furosemide
Brand name: Lasix, Diaqua-2, Lo-Aqua
Synonyms: Furosemide
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Clofibrate-Furosemide Tablets
- Clofibrate-FusePaq Fanatrex
- Clofibrate-FusePaq Synapryn
- Clofibrate-FusePaq Tabradol
- Clofibrate-Fusilev
- Clofibrate-Fusion
- Furosemide Oral Solution-Clolar
- Furosemide Oral Solution-Clomid
- Furosemide Oral Solution-Clomiphene
- Furosemide Oral Solution-Clomiphene Citrate
- Furosemide Oral Solution-Clomipramine
- Furosemide Oral Solution-Clomipramine Capsules