Clofibrate and Rapamune Tablets

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Sirolimus can increase your blood levels of cholesterol and triglycerides. You may need a dose adjustment of clofibrate or more frequent monitoring of your cholesterol levels during treatment with sirolimus. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Higher dosages of lipid-lowering agents may be required during concomitant administration of sirolimus or temsirolimus. Dose-related serum lipid abnormalities, including but not limited to increased serum cholesterol and triglycerides, have been frequently reported in patients treated with sirolimus or temsirolimus.

MANAGEMENT: Close clinical monitoring of serum cholesterol and triglycerides is recommended if sirolimus or temsirolimus is prescribed to patients receiving lipid-lowering agents. Modification of the antihyperlipidemic regimen or dosages may be necessary.

Clofibrate

Generic Name: clofibrate

Brand name:

Synonyms: Clofibrate (Oral)

What is Clofibrate?

Rapamune Tablets

Generic Name: sirolimus

Brand name: Rapamune

Synonyms: Sirolimus

What is Rapamune Tablets?