Clomiphene Citrate and XaQuil XR

• Generic Name: clomiphene
• Dosage Forms: n.a.
• Other Brand Names: Clomid, Serophene

Used to induce ovulation in appropriately selected anovulatory women desiring pregnancy in whom ovulatory dysfunction has been demonstrated.

Optimum results obtained in patients with adequately functioning anterior pituitary gland, adrenals, ovaries, and thyroid, including women with polycystic ovary syndrome, amenorrhea-galactorrhea syndrome, psychogenic amenorrhea, post-oral-contraceptive amenorrhea, and certain cases of secondary amenorrhea of unknown etiology. Better results usually obtained in patients with adequate serum estrogen concentrations; however, reduced serum estrogen concentrations do not always preclude successful therapy.

Use recommended only in women who are not pregnant, without ovarian cysts or ovarian enlargement (unless enlargement is due to polycystic ovarian syndrome), with normal liver function, and with no abnormal vaginal bleeding.

Ineffective in patients with primary pituitary or ovarian failure; not a substitute for appropriate therapy of other conditions that may cause ovulatory dysfunction (e.g., thyroid or adrenal disease).

Manufacturer states that clomiphene is not recommended to induce ovulation associated with in vitro fertilization programs.

• Generic Name: l-methylfolate
• Dosage Forms: n.a.
• Other Brand Names: Deplin, L-Methylfolate Formula, XaQuil XR, L-Methylfolate Formula 75

Folate is a form of B vitamin that occurs naturally in many foods. Folic acid is the man-made form of folate that is added to processed foods or vitamin and mineral supplements. Folate is needed in the human body for production of red blood cells.

A lack (deficiency) of folate in the human body can be caused by certain diseases, by taking certain medications, or by not getting enough folate in your diet. Folate deficiency can lead to decreased red blood cells, or anemia. Folate deficiency can also cause high levels of a certain amino acid in the blood, a condition called hyperhomocysteinemia (HYE-per-HOE-moe-sis-tin-EE-mee-a).

XaQuil XR is a medical food for use in people who have conditions related to folate deficiency. This medicine is also used in people with major depressive disorder who have folate deficiency, or in people with schizophrenia who have hyperhomocysteinemia related to folate deficiency.

XaQuil XR is not an antidepressant or anti-psychotic medication. However, this medicine may enhance the effects of antidepressant medications.

XaQuil XR may also be used for purposes not listed in this medication guide.