Clomipramine Hydrochloride and Klonopin Wafer
Determining the interaction of Clomipramine Hydrochloride and Klonopin Wafer and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using clomiPRAMINE together with clonazePAM may add to dizziness, drowsiness, breathing problems, and other side effects. This may be more likely to occur in older adults or those with a debilitating condition. Talk with your doctor before using clonazePAM together with clomiPRAMINE. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking clonazepam and tricyclic antidepressants. However, one case report has described decreased desipramine levels during concurrent administration with clonazepam. The mechanism is unknown.
MANAGEMENT: Patients should be monitored for excessive or prolonged CNS and respiratory depression. Ambulatory patients should be made aware of the possibility of additive CNS effects (e.g., drowsiness, dizziness, lightheadedness, or confusion) and counseled to avoid activities requiring alertness until they know how these agents affect them. Patients should also be advised to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.
- Deicken RF "Clonazepam-induced reduction in serum desipramine concentration." J Clin Psychopharmacol 8 (1988): 71-3
Generic Name: clomipramine
Brand name: Anafranil
Synonyms: Clomipramine, ClomiPRAMINE
Generic Name: clonazepam
Brand name: Klonopin Wafer, Klonopin
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Clomipramine Hydrochloride-Klonopin Wafers
- Clomipramine Hydrochloride-Klor-Con
- Clomipramine Hydrochloride-Klor-Con M
- Clomipramine Hydrochloride-Klor-Con Powder
- Clomipramine Hydrochloride-Klor-Con Sprinkle
- Clomipramine Hydrochloride-Klor-Con/EF
- Klonopin Wafer-Clonazepam
- Klonopin Wafer-Clonazepam Orally Disintegrating Tablets
- Klonopin Wafer-Clonazepam Tablet Orally Disintegrating
- Klonopin Wafer-Clonazepam Tablets
- Klonopin Wafer-Clonidine
- Klonopin Wafer-Clonidine and Chlorthalidone