Clomipramine Hydrochloride and Pitolisant
Determining the interaction of Clomipramine Hydrochloride and Pitolisant and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.GENERALLY AVOID: Because pitolisant enhances the activity of histaminergic neurons in the brain, centrally acting histamine H1-receptor antagonists or medicines with H1-receptor antagonist properties (e.g., tri- and tetracyclic antidepressants) may impair the efficacy of pitolisant. MANAGEMENT: According to the manufacturer, coadministration of pitolisant with centrally acting H1-receptor antagonists or tri- and tetracyclic antidepressants should be avoided. References Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 "Product Information. Wakix (pitolisant)." Harmony Biosciences, LLC, Plymouth Meeting, PA.
Professional:GENERALLY AVOID: Because pitolisant enhances the activity of histaminergic neurons in the brain, centrally acting histamine H1-receptor antagonists or medicines with H1-receptor antagonist properties (e.g., tri- and tetracyclic antidepressants) may impair the efficacy of pitolisant.
MANAGEMENT: According to the manufacturer, coadministration of pitolisant with centrally acting H1-receptor antagonists or tri- and tetracyclic antidepressants should be avoided.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Wakix (pitolisant)." Harmony Biosciences, LLC, Plymouth Meeting, PA.
Generic Name: clomipramine
Brand name: Anafranil
Synonyms: Clomipramine, ClomiPRAMINE
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Clomipramine Hydrochloride-Pitolisant Hydrochloride
- Clomipramine Hydrochloride-Pitressin
- Clomipramine Hydrochloride-Pitressin Injection
- Clomipramine Hydrochloride-Pitressin Synthetic
- Clomipramine Hydrochloride-Placidyl
- Clomipramine Hydrochloride-Plan B
- Pitolisant-Clonazepam
- Pitolisant-Clonazepam Orally Disintegrating Tablets
- Pitolisant-Clonazepam Tablet Orally Disintegrating
- Pitolisant-Clonazepam Tablets
- Pitolisant-Clonidine
- Pitolisant-Clonidine and Chlorthalidone