Clonazepam Orally Disintegrating Tablets and Kava
Determining the interaction of Clonazepam Orally Disintegrating Tablets and Kava and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Talk to your doctor before using clonazePAM together with kava. Combining these medications can increase the side effects of clonazePAM including drowsiness, confusion, incoordination, difficulty concentrating, and breathing problems. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: A case report suggests that kava may increase the central nervous system adverse effects of benzodiazepines. In the report, a 54-year-old man treated with alprazolam became semicomatose with lethargy and disorientation following self-medication with kava for 3 days. The exact mechanism of interaction is unknown, but an additive or synergistic CNS effect is suspected.
MANAGEMENT: Until further information is available, concomitant use of kava and benzodiazepines is not recommended. Patients on benzodiazepines should be advised to consult their caregiver before using any alternative medicines.
- Pepping J "Kava: Piper methysticum." Am J Health Syst Pharm 56 (1999): 957-60
- Almeida JC, Grimsley EW "Coma from the health food store: interaction between kava and alprazolam." Ann Intern Med 125 (1996): 940-1
- Miller LG "Herbal medicinals: selected clinical considerations focusing on known or potential drug-herb interactions." Arch Intern Med 158 (1998): 2200-11
Generic Name: clonazepam
Brand name: Klonopin, Klonopin Wafer
Synonyms: Clonazepam, ClonazePAM
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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