Clonidine and Thorazine (Chlorpromazine Injection)
Determining the interaction of Clonidine and Thorazine (Chlorpromazine Injection) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using cloNIDine and chlorproMAZINE together can lower your blood pressure. This can cause a slow heartbeat, headaches, dizziness, or feeling like you might pass out. If you take both medications together, tell your doctor if you have any of these symptoms. You may need a dose adjustment or need your blood pressure checked more often if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Case reports suggest that chlorpromazine may potentiate the antihypertensive effects of clonidine. The mechanism is unknown.
MANAGEMENT: Close monitoring for excessive blood pressure reduction is recommended if these drugs are coadministered. Patients should be advised to notify their physician if they experience syncope, orthostasis, or dizziness.
- Markowitz JS, Wells BG, Carson WH "Interactions between antipsychotic and antihypertensive drugs." Ann Pharmacother 29 (1995): 603-9
- Fruncillo RJ, Gibbons WJ, Vlasses PH, Ferguson RK "Severe hypotension associated with concurrent clonidine and antipsychotic medication." Am J Psychiatry 147 (1988): 274
Generic Name: clonidine
Brand name: Catapres, Kapvay, Catapres-TTS, Duraclon, Catapres-TTS-1, Catapres-TTS-2, Catapres-TTS-3
Synonyms: CloNIDine
Generic Name: chlorpromazine
Brand name: Thorazine, Ormazine, Thorazine Spansule
Synonyms: Thorazine (Injection), Thorazine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Clonidine-Thorazine (Chlorpromazine Tablets)
- Clonidine-Thorets
- Clonidine-Thrive gum, lozenge
- Clonidine-Thrivite 19
- Clonidine-Thrombate III
- Clonidine-Thylox Acne Treatment Topical
- Thorazine (Chlorpromazine Injection)-Clonidine and Chlorthalidone
- Thorazine (Chlorpromazine Injection)-Clonidine Epidural
- Thorazine (Chlorpromazine Injection)-Clonidine Epidural Injection
- Thorazine (Chlorpromazine Injection)-Clonidine Extended-Release Tablets
- Thorazine (Chlorpromazine Injection)-Clonidine injection
- Thorazine (Chlorpromazine Injection)-Clonidine Oral, Transdermal