Clonidine and Chlorthalidone and Savella Titration Pack
Determining the interaction of Clonidine and Chlorthalidone and Savella Titration Pack and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Milnacipran may reduce the effects of cloNIDine. You may need a dose adjustment or more frequent monitoring of your blood pressure if you have been taking cloNIDine and are starting treatment with milnacipran. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The antihypertensive effects of clonidine may be antagonized by serotonin-norepinephrine reuptake inhibitors. The proposed mechanism is opposing effects on adrenergic alpha-2 receptors.
MANAGEMENT: If concomitant use cannot be avoided, monitoring for altered efficacy of clonidine is recommended. In some cases, the dosage of clonidine may require upward adjustment.
- "Product Information. Savella (milnacipran)." Forest Pharmaceuticals, St. Louis, MO.
Generic Name: chlorthalidone / clonidine
Brand name: Clorpres
Synonyms: n.a.
Generic Name: milnacipran
Brand name: Savella, Savella Titration Pack
Synonyms: Savella
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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