Clorazepate and Prilocaine and Epinephrine
Determining the interaction of Clorazepate and Prilocaine and Epinephrine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using clorazepate together with prilocaine can increase nervous system side effects such as dizziness, drowsiness, and confusion. Avoid activities requiring mental alertness such as driving or operating hazardous machinery until the effects of these medications have worn off. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.
Professional:MONITOR: The concomitant use of local anesthetics and benzodiazepines may have additive CNS-depressant effects. Both types of drugs are CNS depressants.
MANAGEMENT: Caution is advised during concurrent use. Patients should be monitored for potentially excessive or prolonged CNS depression and other CNS adverse effects. Dosage adjustments may be required.
- Cerner Multum, Inc. "Australian Product Information." O 0
- Agencia EspaƱola de Medicamentos y Productos Sanitarios Healthcare "Centro de informaciĆ³n online de medicamentos de la AEMPS - CIMA. Available from: URL: https://cima.aemps.es/cima/publico/home.html." ([2018]):
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: clorazepate
Brand name: Tranxene T-Tab, Tranxene SD
Synonyms: n.a.
Generic Name: epinephrine / prilocaine
Brand name: Citanest Forte Dental
Synonyms: Prilocaine with Epinephrine Injection
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Clorazepate-Prilocaine Hydrochloride
- Clorazepate-Prilocaine Hydrochloride Injection
- Clorazepate-Prilocaine with Epinephrine Injection
- Clorazepate-Prilolid
- Clorazepate-Prilosec
- Clorazepate-Prilosec (Omeprazole Delayed-Release Capsules)
- Prilocaine and Epinephrine-Clorazepate Dipotassium
- Prilocaine and Epinephrine-Clorotekal
- Prilocaine and Epinephrine-Clorpres
- Prilocaine and Epinephrine-Clotrimazole
- Prilocaine and Epinephrine-Clotrimazole (Oral)
- Prilocaine and Epinephrine-Clotrimazole Betamethasone Cream