Clozaril and Horse chestnut

• Generic Name: clozapine
• Dosage Forms: tablet
• Other Brand Names: Clozaril, Fazaclo, Versacloz, Clopine, CloZAPine Synthon, Denzapine, Zaponex

Clozaril (clozapine) is an antipsychotic medication. It works by changing the actions of chemicals in the brain.

Clozaril is used to treat severe schizophrenia, or to reduce the risk of suicidal behavior in people with schizophrenia or similar disorders.

Clozaril is available only from a certified pharmacy under a special program.

Clozaril may also be used for indications not mentioned in this review.

• Generic Name: horse chestnut
• Dosage Forms: n.a.
• Other Brand Names: Venastat

Horse chestnut is a plant also known as Aescin, Aesculus hippocastanum, Buckeye, Castaño de Indias, Châtaignier de Mer, Châtaignier des Chevaux, Escine, Faux-Châtaignier, Hippocastani, Hippocastanum Vulgare Gaertn, Marron Europeen, Marronnier, Spanish Chestnut, Venostasin Retard, Venostat, White Chestnut, and other names.

Horse chestnut has been used in alternative medicine and is likely effective in treating some symptoms of chronic venous insufficiency (decreased blood flow return from the feet and legs back to the heart). These symptoms include leg pain or tenderness, varicose veins, itching or swelling in the legs, and fluid retention (puffy or swollen ankles or feet).

Other uses not proven with research have included fever, cough, diarrhea, hemorrhoids, enlarged prostate, menstrual cramps, and swelling caused by arthritis, sprains, or bone fractures.

It is not certain whether horse chestnut is effective in treating any medical condition. Medicinal use of this product has not been approved by the FDA. Horse chestnut should not be used in place of medication prescribed for you by your doctor.

Horse chestnut is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Horse chestnut may also be used for purposes not listed in this product guide.