Clozaril and Onasemnogene Abeparvovec

• Generic Name: clozapine
• Dosage Forms: tablet
• Other Brand Names: Clozaril, Fazaclo, Versacloz, Clopine, CloZAPine Synthon, Denzapine, Zaponex

Clozaril (clozapine) is an antipsychotic medication. It works by changing the actions of chemicals in the brain.

Clozaril is used to treat severe schizophrenia, or to reduce the risk of suicidal behavior in people with schizophrenia or similar disorders.

Clozaril is available only from a certified pharmacy under a special program.

Clozaril may also be used for indications not mentioned in this review.

• Generic Name: onasemnogene abeparvovec
• Dosage Forms: n.a.
• Other Brand Names: Zolgensma, Zolgensma

Onasemnogene abeparvovec is used to treat spinal muscular atrophy in children younger than 2 years old who have a specific gene mutation that affects nerve signals to the muscles.

onasemnogene abeparvovec may not be effective in a child who is completely paralyzed or is dependent on a ventilator for breathing.

Onasemnogene abeparvovec may also be used for purposes not listed in this medication guide.