Cobicistat and Hyzaar

• Generic Name: cobicistat
• Dosage Forms: n.a.
• Other Brand Names: Tybost

Cobicistat is used to increase your blood levels of these medicines, helping to make them safer and more effective at lower doses.

Cobicistat is given together with atazanavir (Reyataz) or darunavir (Prezista) to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS).

When given with atazanavir, cobicistat is for use in adults and in children who weigh at least 77 pounds (35 kilograms). When given with darunavir, cobicistat is for use only in adults.

Cobicistat is not an antiviral medicine and will not treat HIV or AIDS. Cobicistat is given only to help increase your blood levels of atazanavir or darunavir.

Cobicistat may also be used for purposes not listed in this medication guide.

• Generic Name: hydrochlorothiazide / losartan
• Dosage Forms: tablet, film coated
• Other Brand Names: Hyzaar

Hyzaar contains a combination of hydrochlorothiazide and losartan. Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Losartan is an angiotensin II receptor antagonist (sometimes called an ARB blocker). Losartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

Hyzaar is used to treat high blood pressure (hypertension).

Hyzaar is also used to lower the risk of stroke in certain people with heart disease.