Cobicistat and darunavir and Videx EC
Determining the interaction of Cobicistat and darunavir and Videx EC and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using didanosine together with darunavir can alter the effects of darunavir. Darunavir should be administered with food, which may adversely affect the absorption of didanosine due to increased acid in the stomach induced by food intake. Darunavir should be taken with food at least two hours before or one hour after didanosine. Contact your doctor if your condition worsens. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSING INTERVAL: Combination products containing darunavir should be administered with food, which may adversely affect the absorption of didanosine during concurrent administration due to increased acid in the stomach induced by food intake.
MANAGEMENT: Combination products containing darunavir, including darunavir-ritonavir and darunavir-cobicistat should be taken with food at least two hours before or one hour after didanosine.
- "Product Information. Prezista (darunavir)." Ortho Biotech Inc, Bridgewater, NJ.
Generic Name: cobicistat / darunavir
Brand name: Prezcobix
Synonyms: Darunavir and Cobicistat
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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