Codar GF and Cordarone
Determining the interaction of Codar GF and Cordarone and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Amiodarone may reduce the effectiveness of codeine. You may need a dose adjustment if you have been taking codeine and are starting treatment with amiodarone. Let your doctor know if your condition changes or you experience reduced or inadequate relief of your symptoms. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Drugs that are inhibitors of CYP450 2D6 may interfere with the analgesic effect of codeine. The mechanism is decreased in vivo conversion of codeine to morphine, a metabolic reaction mediated by CYP450 2D6.
MANAGEMENT: The possibility of reduced or inadequate pain relief should be considered in patients receiving codeine with drugs that inhibit CYP450 2D6. An increase in the codeine dosage or a different analgesic agent may be necessary in patients requiring therapy with CYP450 2D6 inhibitors.
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Generic Name: codeine / guaifenesin
Brand name: Allfen CD, Cheracol with Codeine, Cheratussin AC, Codar GF, Duraganidin NR, Guaiatussin AC, Iophen-C NR, Mar-cof CG, M-Clear, Mytussin AC, Relcof C, Guaifenesin AC Liquid, Iophen C-NR, Mar-cof CG, Ninjacof-XG, Virtussin A/C
Synonyms: n.a.
Generic Name: amiodarone
Brand name: Cordarone, Pacerone, Nexterone
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Codar GF-Cordarone injection
- Codar GF-Cordarone IV Intravenous
- Codar GF-Cordran
- Codar GF-Cordran (Flurandrenolide Cream and Ointment)
- Codar GF-Cordran (Flurandrenolide Lotion)
- Codar GF-Cordran Lotion
- Cordarone-Codeine
- Cordarone-Codeine and Chlorpheniramine
- Cordarone-Codeine and Chlorpheniramine ER Tablets
- Cordarone-Codeine and Chlorpheniramine Extended-Release Suspension
- Cordarone-Codeine and Chlorpheniramine Extended-Release Tablets
- Cordarone-Codeine and Chlorpheniramine Liquid