Codeine, phenylephrine, and promethazine and Oxybutynin Gel
Determining the interaction of Codeine, phenylephrine, and promethazine and Oxybutynin Gel and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using codeine together with oxybutynin can increase the effects of either medication. This can commonly cause dizziness, drowsiness, difficulty concentrating, dry mouth, abdominal cramping, and constipation. Some people may also experience some impairment in thinking and judgment. Avoid driving or operating hazardous machinery until you know how the medications affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration of narcotic analgesics with anticholinergic agents may result in additive central nervous system (CNS) and gastrointestinal (GI) adverse effects, and increase the risk of severe constipation or paralytic ileus and CNS depression.
MANAGEMENT: If concomitant use cannot be avoided, patients should be monitored for potentially excessive or prolonged CNS depression and constipation. Ambulatory patients should be counseled to avoid activities requiring mental alertness until they know how these agents affect them.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: codeine / phenylephrine / promethazine
Brand name: Promethazine VC with Codeine, Phenergan VC with Codeine, M-Phen
Synonyms: Promethazine, Phenylephrine, and Codeine
Generic Name: oxybutynin
Brand name: Ditropan XL, Anturol, Gelnique, Oxytrol
Synonyms: Oxybutynin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Codeine, phenylephrine, and promethazine-Oxybutynin Oral Solution
- Codeine, phenylephrine, and promethazine-Oxybutynin Syrup
- Codeine, phenylephrine, and promethazine-Oxybutynin Tablets
- Codeine, phenylephrine, and promethazine-Oxybutynin transdermal
- Codeine, phenylephrine, and promethazine-Oxybutynin Transdermal System
- Codeine, phenylephrine, and promethazine-Oxycodone
- Oxybutynin Gel-Codeine, phenylephrine, and triprolidine
- Oxybutynin Gel-Codeprex
- Oxybutynin Gel-CodiClear DH
- Oxybutynin Gel-Codimal DM
- Oxybutynin Gel-Codituss DM
- Oxybutynin Gel-Coditussin AC