CodiClear DH and Ticlopidine Hydrochloride

• Generic Name: guaifenesin / hydrocodone
• Dosage Forms: n.a.
• Other Brand Names: Xtrelus

Guaifenesin and hydrocodone combination is used to relieve cough and nasal congestion associated with the common cold.

Hydrocodone is a narcotic antitussive (cough suppressant). It acts directly on the cough center in the brain to relieve cough. Guaifenesin is used to help clear mucus or phlegm from the chest when you have congestion from a cold or flu. It works by thinning the mucus or phlegm in the lungs.

This medicine is available only with your doctor's prescription.

• Generic Name: ticlopidine
• Dosage Forms: n.a.
• Other Brand Names: Ticlid

Used to reduce the risk of fatal or nonfatal thrombotic stroke in patients who have had either a previous completed thrombotic stroke or stroke precursors (e.g., TIA, transient monocular or partial blindness [amaurosis fugax], reversible ischemic neurologic deficit, minor stroke).

Because of potentially life-threatening adverse effects (see Boxed Warning), reserve for patients who are unable to tolerate or have hypersensitivity to aspirin or those who have failed to respond to aspirin therapy where indicated to prevent stroke.

The American College of Chest Physicians (ACCP) states that use of ticlopidine for secondary prevention of stroke has become severely limited because of the risk of serious adverse effects and the availability of safer antiplatelet agents.

Used as an adjunct to aspirin therapy to reduce the incidence of subacute stent thrombosis after PCI with successful coronary artery stent placement.

Ticlopidine for this use largely has been replaced by other antiplatelet agents. ACCP and other experts currently recommend dual-drug antiplatelet therapy with other P2Y12-receptor antagonists (e.g., clopidogrel, prasugrel, ticagrelor) and aspirin in patients undergoing PCI with stent placement.